In Dry AMD, where are drusen located relative to Bruch's membrane?

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Multiple Choice

In Dry AMD, where are drusen located relative to Bruch's membrane?

Explanation:
Drusen are extracellular deposits that form at the interface between the retinal pigment epithelium (RPE) and Bruch's membrane. This place is on the retinal side of Bruch's membrane, so they sit above Bruch's membrane. Bruch's membrane separates this space from the choroid, which is why drusen are not located in the choroid, within Bruch's membrane, or below Bruch's membrane. Their presence between the RPE and Bruch's membrane can disrupt exchange of nutrients and waste, contributing to dry AMD progression.

Drusen are extracellular deposits that form at the interface between the retinal pigment epithelium (RPE) and Bruch's membrane. This place is on the retinal side of Bruch's membrane, so they sit above Bruch's membrane. Bruch's membrane separates this space from the choroid, which is why drusen are not located in the choroid, within Bruch's membrane, or below Bruch's membrane. Their presence between the RPE and Bruch's membrane can disrupt exchange of nutrients and waste, contributing to dry AMD progression.

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